When the SARS-CoV-2 pandemic took hold, a lot of scientists had to shut down their labs, or at least significantly slow down their pace of research. Our lab was no exception. On the other hand, our Immune Dysregulation team at CHOP sprung into action to try to understand the immune mechanisms of disease in children infected with the virus. This work has produced a number of publications, on which many I have had the privilege to be co-senior author. We are continuing to generate and analyze an enormous amount of data from this work, and have a number of manuscripts under review at the moment as well. That link should update with new papers as they hit Pubmed, so check back to see the most recent work our group has published. Hopefully, through science, we will beat this virus and come out the other end with even more knowledge about how pathogens result in immune dysregulation and disease that will help us in the future. In the meantime, get vaccinated, use appropriate personal protective equipment, and wash your hands.